Year 11 / Exchange of nutrients and wastes
Catalysts in living systems.
Enzymes are biological catalysts. Their active sites bind suitable substrates and lower the activation energy of a reaction. Digestive enzymes break large food molecules into smaller products that can cross membranes.
As temperature rises, molecular collisions tend to increase until an optimum is reached. High temperatures can alter the active site and reduce enzyme activity. pH can also change the shape and charge of the active site.
Enzyme activity
Explore: Adjust temperature and compare the optimum with the denatured region.
An enzyme works fastest at 37 °C but slowly at 70 °C.
- The initial rise reflects more frequent productive collisions.
- At 70 °C, loss of active-site shape can prevent substrate binding.
Assumed knowledge
Basic chemical reactions.
Learning checkpoints & source
YOUR LEARNING CHECKPOINT- Explain enzyme specificity.
- Predict how temperature changes reaction rate.
READY TO TRY IT?